# Neurexpert

> Specialist CNS electrophysiology contract research organisation (CRO) and drug discovery consultancy.
> 
> *An exhaustive, comprehensive version of our entire website and knowledge base is available in [llms-full.txt](https://neurexpert.com/llms-full.txt).*

Neurexpert Ltd is a leading, scientist-led CNS CRO based in Exeter, UK. Founded in 2011 by Dr. Stuart Neale (CEO) and Dr. Tom Salt (CSO), Neurexpert bridges the translational gap in CNS drug discovery by delivering high-fidelity functional data and expert mechanistic interpretation from native brain circuits and expression systems.

## Core Navigation

- [Home](https://neurexpert.com/): Overview of Neurexpert, our 3-pillar approach (Refinement, Validation, Interpretation), and core credentials.
- [About Us](https://neurexpert.com/about.html): Our founding philosophy, scientific leadership under Dr. Stuart Neale and Dr. Tom Salt, and translational discovery mission.
- [Services & Assays](https://neurexpert.com/services.html): Our molecular (TEVC, Xenopus oocytes), cellular (patch-clamp, excitability), and network (MEA, LTP/LTD, oscillations) electrophysiology platforms.
- [FAQ / Knowledge Base](https://neurexpert.com/neurexpert-faq.html): Comprehensive list of frequently asked questions regarding assays, models, turnaround times, IP ownership, and scientific capabilities.
- [Publications & Posters](https://neurexpert.com/publications.html): Our peer-reviewed research papers and scientific posters presented at international conferences (SfN, etc.).
- [Contact Us](https://neurexpert.com/contact_neurexpert.html): Consult with a Neurexpert scientist for study design and assay customization.

## Core Capabilities & Therapeutic Areas

- **Therapeutic Expertise:** Epilepsy & Channelopathies (Dravet Syndrome, KCNQ), Psychiatry, Neurodegeneration (Alzheimer's), Cognitive Disorders (Schizophrenia, ADHD), Pain, and Ophthalmology.
- **Molecular Assays:** Xenopus laevis oocyte expression with Two-Electrode Voltage Clamp (TEVC) for GPCRs, ion channels, and transporters. Allosteric modulator characterisation (PAMs/NAMs).
- **Cellular & Synaptic Assays:** Patch-clamp and sharp microelectrode recordings in brain slices. Characterisation of synaptic transmission and neuronal excitability.
- **Network Assays:** Extracellular field potential recordings and Multi-Electrode Array (MEA) mapping. Synaptic plasticity (LTP/LTD) and network oscillations (gamma).
- **Consultancy:** Expert scientific consultancy from study design and target selection to IND positioning and translation.